CONFERENCE COVERAGE SERIES
Society for Neuroscience Annual Meeting 2013
San Diego, CA, U.S.A.
09 – 13 November 2013
Researchers Revel in C9ORF72 Advances at RNA Symposium
The latest news on C9ORF72 includes a genetic modifier, various animal models, and a potential treatment to untangle stable, guanine-based structures formed by expanded repeats.
Profilin-1 Links Cytoskeleton and RNA Aggregation in ALS
Researchers find an actin-binding protein in stress granules, linking the cytoskeleton and RNA sequestration in the pathology of amyotrophic lateral sclerosis.
The Four Stages of TDP-43 Proteinopathy
Researchers propose four stages of TDP-43 pathology based on the spread of the protein through the brain.
Blocking a MicroRNA Slows Motor Neuron Disease in Mice
With several microRNAs being overly active in ALS, an antisense therapy to one slows the disease in mice, apparently by reducing neuroinflammation.
Glial Cells Refine Neural Circuits
New research reveals fundamental roles for astrocytes and microglia in shaping neural circuits.
Innate Immune Cells Enlisted to Clear Amyloid, Fight Disease
Scientists are tweaking immune pathways to scavenge amyloid and curb symptoms in Alzheimer’s mice.
Is Dendritic Tau to Blame for AD-Related Hyperexcitability?
In neurodegenerative disease, tau is in the dendrites, and scientists are beginning to flesh out ways to block what it does there.