Alzpedia
SNCA (α-synuclein)
Synonyms: PD1, NACP, PARK1, PARK
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References
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Further Reading
News
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- Excess α-Synuclein Sends Synapses Sputtering
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Papers
- Jones DR, Moussaud S, McLean P. Targeting heat shock proteins to modulate α-synuclein toxicity. Ther Adv Neurol Disord. 2014 Jan;7(1):33-51. PubMed.
- Jucker M, Walker LC. Self-propagation of pathogenic protein aggregates in neurodegenerative diseases. Nature. 2013 Sep 5;501(7465):45-51. PubMed.
- Irwin DJ, Lee VM, Trojanowski JQ. Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies. Nat Rev Neurosci. 2013 Sep;14(9):626-36. PubMed.
- Manzoni C, Lewis PA. Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies. FASEB J. 2013 May 16; PubMed.
- George S, Rey NL, Reichenbach N, Steiner JA, Brundin P. α-Synuclein: the long distance runner. Brain Pathol. 2013 May;23(3):350-7. PubMed.
- Puschmann A. Monogenic Parkinson's disease and parkinsonism: clinical phenotypes and frequencies of known mutations. Parkinsonism Relat Disord. 2013 Apr;19(4):407-15. PubMed.