Do Overloaded Microglia Smother Stressed Neurons?
In mice with prion disease, microglia shifted from gobbling up misfolded protein to engulfing flagging neurons. This change coincided with symptom onset.
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Glial Cell Communities Conspire to Drive Alzheimer’s Disease
Transcriptomes of more than 400 postmortem brains reveal microglia and astrocyte subtypes that collaborate to precipitate pathologic changes.
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