New Alzheimer's Journal
Scientists often complain that scientific journals take too long to review manuscripts, and that subscription prices are unaffordable. A new journal devoted to Alzheimer's disease research, Alzheimer's Reports...
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Normal Presenilin-1 May Inhibit Amyloid β Formation
Researchers trying to study the role of presenilin-1 (PS1) in Alzheimer's pathogenesis have been stymied by the fact that presenilin knockout mice die before birth...
Caspase's Role in Apoptosis Clarified
Two recent papers describe the processes involved in the final stages of apoptotic cell death. During apoptosis, enzymes known as caspases break down cellular proteins, causing severe morphological changes and cell shrinkage...
Copper-binding Function for Prion Protein?
A pathologic form of prion protein is believed to cause scrapie, bovine spongiform encephalopathy and Creutzfeldt-Jakob disease. The normal function of prion protein is yet unknown, but a recent study by Hans Kretzschmar...
Proteoglycans Inhibit Axon Regeneration
Why is the adult mammalian central nervous system unable to regenerate damaged axons? Scarring of glial tissue may be a factor...
New Microscope Reveals Alignment of Molecules in Living Cells
An innovative microscope has been developed which provides scientists with a new window through which to explore the dynamics of molecular order and disorder in living cells and other quasi-liquid systems...
Entire Genome Yields to a Chip
Researchers at California-based Affymetrix have analyzed the activity of every gene in the yeast genome in a single experiment using a new "DNA chip." This remarkable technological feat hints of a future...
Two New Genetic Risk Factors for Late-Onset Alzheimer’s Disease
Scientists working in Oxford University and Duke University Medical Center this week reported the discovery of two new genetic risk factors for late-onset Alzheimer’s disease...
TGF-β1 Linked to Plaque Formation
A history of brain injury raises a person’s risk of Alzheimer’s disease, and many researchers now suspect that the brain’s inflammatory responses to injury may magnify the neurodegenerative process...
Antibodies Find a New Variety of Alzheimer's Plaque
Researchers in Dr. John Q. Trojanowski's lab at the University of Pennsylvania have discovered a new type of lesion in the brains of Alzheimer's patients...
MEDLINE Now Free to the Public
The National Library of Medicine's MEDLINE database is now accessible free to the general public through PubMed and Internet Grateful Med. Hot links to IGM and PubMed are available on the NLM home page...
Possible New Succeptability Genes for Alzheimer's Disease
Put these two facts together: brain energy metabolism is abnormally low in Alzheimer's patients, and if <a href="http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8710088&form=6&db=m&Dopt=r">your mother had Alzheimer's</a> you are more likely to develop it than if your father had Alzheimer's...
Vitamin E, Antioxidants and Alzheimer's Disease
Results released today of a study published in the New England Journal of Medicine indicated that large doses of vitamin E may delay the time at which late-stage Alzheimer's patients must be institutionalized.
Clues from the Colombian Countryside
An enormous extended family living in a rural community in Colombia could provide new insights into environmental and genetic factors contributing to Alzheimer’s disease. All family members who were diagnosed...
Ibuprofen Linked to Reduced Alzheimer's Risk
Ibuprofen and related drugs may reduce a person’s risk of getting Alzheimer’s disease by 30 to 60 percent, according to a new study by researchers at Johns Hopkins University and the National Institute on Aging...
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