MODEL-AD Probably Has Something for You
The consortium has cranked out dozens of mouse models of late-onset AD for the research community. Strains carry humanized Aβ and tau, and a growing list of risk variants.
ALL NEWS
6066 RESULTS
Sort By:
- Most Recent
- Most Commented
Do Overloaded Microglia Smother Stressed Neurons?
In mice with prion disease, microglia shifted from gobbling up misfolded protein to engulfing flagging neurons. This change coincided with symptom onset.
Remember Amyloid-eta? A Decade Later, News on a Physiological Function
To modulate synapses, Aη weakens ion flux through glutamate receptors and strengthens their non-ionotropic signaling. This dual action is a first, say scientists.
Reconceptualizing the BBB: Is It Time to Swap ‘Barrier’ for ‘Border'?
The adaptive nature of the interface between blood and brain led some scientists to envision it more like an actively managed border crossing, not a wall.
Chimeric Protein Dephosphorylates Tau, Improves Memory
In tauopathy mice, a peptide construct recruited protein phosphatase 1 to tau. Dephosphorylation lowered total tau, restoring synaptic density and memory.
Brave New World? Technology in Dementia Diagnosis, Care
Do you associate technology with youth? Picture this woman doing an automated telephone assessment and think again. Modern gadgets stand poised to transform dementia research and care. Researchers are harnessing the power of computers, digital cameras, an
Current Filters
No filters selected