Ever since amyloid-β (Aβ) was identified as the major component in amyloid plaques, scientists have been trying to decipher just exactly what the little peptide does. Most researchers would agree that Aβ is toxic to cells, but some are still skeptical. Ev
Are you a physician or caregiver thirsting for an update on the latest research on Alzheimer disease, or are you a basic researcher curious about the latest advances in clinical diagnosis and care? Tom Wisniewski and Marcin Sadowski led this live discus
Our thanks to the Journal of Gerontology for granting permission to post the full text article. Natalie Rasgon led this live discussion on 6 July 2005. Readers are invited to submit additional comments by using our Comments form at the bottom of the page.
This live discussion was held on the paper by O'Doherty et al., in Science, on "An aneuploid mouse strain carrying human chromosome 21 with down syndrome phenotypes." Lizzy Fisher and Victor Tybulewicz led this live discussion on 14 October
In a paper just published in the inaugural issue of the new journal, Alzheimer's & Dementia, Claudio Costantini, Rekha Kolasani, and Luigi Puglielli argue that the lipids ceramide and cholesterol may provide metabolic links between AD and aging.
See also our Drug Development Database and Tutorial. Howard Fillit, Jordan Tang, Frank Longo, Eli Michaelis, and Jens Eckstein led this live discussion on 16 September 2005. Readers are invited to submit additional comments by using our Comments form at t
The topic is an apt one to launch the new year: what factors in daily life can reduce one's risk of Alzheimer's disease? To fire up your neural networks, you are invited to read the recent review (download pdf) by Kathryn Jedrziewski, Virginia L
Katrina Gwinn-Hardy led this Web seminar and discussion on the whole genome study of Parkinson disease which was published recently in Lancet Neurology. Co-author Gwinn-Hardy presented the findings and introduced some discussion topics around data sharing
The amyloid-β-yielding extracellular domain of APP has gotten most of the attention over the last decade or so, but inside the cell there is a large cytoplasmic fragment that might be the key to understanding the true nature of APP. Sanjay Pimplikar led
Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.