New Theories of Presenilin Function

12 Dec 2000

http://www.alzforum.org/res/for/journal/detail.asp?liveID=106 γ-Secretase

Cholesterol and Alzheimer's—Charging Fast But Still at a Distance from Solid Answers

• 3 Comments

19 Nov 2002

http://www.alzforum.org/res/for/journal/detail.asp?liveID=87 Cholesterol

Cell Death: Time to Push It Out of the Doldrums

• 10 Comments

10 Sep 2004

http://www.alzforum.org/res/for/journal/detail.asp?liveID=61 yshen Yong Shen Cell Death

Mice on Trial? Issues in the Design of Drug Studies

• 3 Comments

02 Jun 2008

http://www.alzforum.org/res/for/journal/detail.asp?liveID=168 Sean Scott Research Models

Cell Cycle Hypothesis Pedaling into Mainstream Acceptance? Results in Fly, Mouse Models Warrant a Second Look

• 4 Comments

12 Apr 2006

12:00am Alzheimer's Disease http://www.alzforum.org/res/for/journal/detail.asp?liveID=45 vkhurana Vik

BDNF and Alzheimer's Disease—What's the Connection?

25 Nov 2003

http://www.alzforum.org/res/for/journal/detail.asp?liveID=75 Growth Factors and Growth Factor Receptors

Beta-Catenin and PS1

13 Aug 1999

Chris Weihl, with Bruce Yankner, Benjamin Wolozin, Eddie Koo, and Kenneth Kosik led this live discussion on 13 August 1999. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion

Vascular Factors in Alzheimer's Disease

21 Apr 2004

00:00 Alzheimer's Disease http://www.alzforum.org/res/for/journal/detail.asp?liveID=68 Jack de la

Probing PPARγ? Agonists: Could Diabetes Drugs Treat Alzheimer's Disease?

• 1 Comment

16 Dec 2002

http://www.alzforum.org/res/for/journal/detail.asp?liveID=85 Elena Galea dlfeins Diabetes Related PPARγ

Alzheimer Presenilins in the Nuclear Membrane, Interphase Kinetochores, and Centrosomes Suggest a Role in Chromosome Segregation

20 Mar 1998

Marc Paradis led this live discussion on 20 March 1998. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Paper under Discussion: Li JH, Xu M, Zhou H. Ma J. and Potter H. Alzheimer presenilins in the n

Generation of an Apoptotic Intracellular Peptide by γ-secretase Cleavage of Alzheimer's β-amyloid Precursor Protein

20 Sep 2000

Benjamin Wolozin, with Luciano D'Adamio and Eddie Koo, led this live discussion on 20 September 2000. Readers are invited to submit additional comments by using our Comments form at the bottom of the page.   Journal of Alzheimer's Disease. 2000;

The Role of ApoE in Alzheimer's Disease: An Alternative View

11 Dec 2001

Keith Crutcher led this live discussion on 11 December 2001. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held on 11 December 2001. Participants: Keith Crutcher, Nico S

The Cell Cycle and Alzheimer’s Disease—Let's Unite for Division!

• 6 Comments

07 Aug 2002

Inez Vincent led this live discussion on 7 August 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. See diagram from Inez Vincent Transcript: Live discussion held 20 May 2002 at 12 noon. Particip

Targeting Tumor Necrosis Factor—A Therapeutic Strategy for AD

• 2 Comments

29 May 2008

Recent experience with an anti-TNFα drug has made scientists suspect that inhibiting this proinflammatory cytokine may hold promise as a protective treatment for diseases that feature neuroinflammation, such as Alzheimer's. Yet it is unclear how best

Not Dead Yet: Estrogen Deserves Another Chance

• 1 Comment

28 Jan 2006

You may think the Women’s Health Study has sounded the death knell for estrogen replacement therapy, but actually, the idea is showing new signs of life. A second-generation approach with better compounds may warrant continued investment, and yet, how doe