Generation of an Apoptotic Intracellular Peptide by γ-secretase Cleavage of Alzheimer's β-amyloid Precursor Protein

20 Sep 2000

Benjamin Wolozin, with Luciano D'Adamio and Eddie Koo, led this live discussion on 20 September 2000. Readers are invited to submit additional comments by using our Comments form at the bottom of the page.   Journal of Alzheimer's Disease. 2000;

New Theories of Presenilin Function

12 Dec 2000

http://www.alzforum.org/res/for/journal/detail.asp?liveID=106 γ-Secretase

The Role of ApoE in Alzheimer's Disease: An Alternative View

11 Dec 2001

Keith Crutcher led this live discussion on 11 December 2001. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held on 11 December 2001. Participants: Keith Crutcher, Nico S

Neural Stem Cells to the Rescue—Can Neuroreplacement Ever Become a Treatment for Alzheimer's?

09 Jul 2002

Neuroscience 2000, http://sfn.ScholarOne.com/itin2001/; search by Sugaya), unsupplemented, serum-free

Alzheimer Genes in Cortical Development: How Do Their Prenatal Functions Relate to Dementia?

12 Jul 2002

rbowen@voyagerpharma.com Jie Shen: I am not sure about the relationship between PS and apoptosis, since we did not see

From Here to There: AβPP as an Axonal Transport Receptor—How Could This Explain Neurodegeneration in AD?

15 Jul 2002

http://www.alzforum.org/res/for/journal/detail.asp?liveID=91 Cell Death APP

Will Probing Flies and Worms Bear Fruit in the Search for New Genes Involved in Alzheimer's?

29 Oct 2002

http://www.alzforum.org/res/for/journal/detail.asp?liveID=88 Research Models

CAA: We All Know It's There, But Just What Is It Doing in Alzheimer's?

12 Mar 2003

Alzheimer's Disease http://www.alzforum.org/res/for/journal/detail.asp?liveID=84 sgreenberg Steven Greenberg

RNAi in Neurodegenerative Diseases—What's the Therapeutic Potential?

18 Mar 2003

0 Tuesday, March 18, 2003- 00:00 http://www.alzforum.org/res/for/journal/detail.asp?liveID=83 zuoshang.xu

Cholinergic Plasticity in Hippocampus of Individuals with Mild Cognitive Impairment: Correlation with Alzheimer's Neuropathology

19 May 2003

http://www.alzforum.org/res/for/journal/detail.asp?liveID=81 Acetylcholine

Therapeutic Nihilism: Widespread Yet Passé? AD Acetylcholinesterase Inhibitors Are Better Than Their Reputation

14 Oct 2003

http://www.alzforum.org/res/for/journal/detail.asp?liveID=77 morrisj John C. Morris Therapeutics Acetylcholine

Novel Substrates for BACE1 Beg the Question: What's the Biological Function of β-Secretase?

17 Dec 2003

17, 2003- 00:00 http://www.alzforum.org/res/for/journal/detail.asp?liveID=73 Stefan.Lichtenthaler

Clioquinol Trial Postmortem: Does Blocking Metal-Aβ Interactions Work?

15 Jan 2004

http://www.alzforum.org/res/for/journal/detail.asp?liveID=72 bush Ashley Bush Clinical Research Oxidative Stress Therapeutics Aβ

Minority Views and Professional Responsibilities—Scientists Air Their Views

10 Mar 2004

http://www.alzforum.org/res/for/journal/detail.asp?liveID=70 george.perry George Perry

Stem Cell Therapies for Neurodegenerative Disease: How Should We Push Ahead?

30 Mar 2004

http://www.alzforum.org/res/for/journal/detail.asp?liveID=69 Aging Stem Cells/Neurogenesis Therapeutics