β Amyloid Degradation: The Forgotten Half of Alzheimer's Disease

• 7 Comments

12 Sep 2002

Malcolm Leissring and Wesley Farris led this live discussion on 12 September 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 12 September 2002 with Wesley Farri

The Cell Cycle and Alzheimer’s Disease—Let's Unite for Division!

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07 Aug 2002

Inez Vincent led this live discussion on 7 August 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. See diagram from Inez Vincent Transcript: Live discussion held 20 May 2002 at 12 noon. Particip

Cerebrometabolic Deficiency in Alzheimer's Disease

• 2 Comments

22 Apr 2002

J Molec Neurosci 2001;(17):361-369. Abstract. 26. Curti D, Rognoni F, Gasparini L, Cattaneo A, Paolillo M,

The Neuroplasticity Theory of Alzheimer's Disease

• 1 Comment

08 Apr 2002

dependent secretion of b-amyloid: roles of b-amyloid in synaptic transmission. Soc Neurosci Abstr. 26, 491

Alzheimer Immunotherapy Trial Grounded: Time to Reassess Safety and Vaccine Design

• 3 Comments

05 Mar 2002

Giulio Maria Pasinetti led this live discussion on 5 March 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page.     Background Reading by Giulio Maria Pasinetti et al. (pdf file: download free Acrob

Picking up the Pieces of Parkin

• 1 Comment

17 Jan 2002

Dubiel, W., and Gordon, C., Regulatory subunit interactions of the 26S proteasome, a complex problem.

The Role of ApoE in Alzheimer's Disease: An Alternative View

11 Dec 2001

further reading: (Teter et al., 1999; Fan et al. 2002; Champagne et al., Soc. Neurosci Abstract 26, 1546;

Calcium Signaling Deficit in the Origin of Alzheimer's Disease

• 8 Comments

07 Sep 2001

difficult to measure? Cell Calcium. 1999 Sep-Oct;26(3-4):149-54. Abstract. 9. Chen M, Durr J, Fernandez HL.

New Theories of Presenilin Function

12 Dec 2000

Neurobiol Dis. 2000 Apr; 7:119-26. Abstract. Beher, D., C. Elle, J. Underwood, J.B. Davis, R. Ward, E.

Generation of an Apoptotic Intracellular Peptide by γ-secretase Cleavage of Alzheimer's β-amyloid Precursor Protein

20 Sep 2000

those recently published (26), which demonstrated that C31, a COOH-terminal polypeptide corresponding to

Protofibrillar Aβ in Alzheimer's Disease

17 Feb 2000

system neurotoxins. Proc Natl Acad Sci U S A 1998 May 26;95(11):6448-53. Abstract. Comments and questions

Pin1, Tau and the Cell Cycle in Alzheimer Disease

03 Aug 1999

modules. Science 1999 Feb 26;283:1325-1328. Abstrac t. 9. Nagy Z, Esiri MM, Cato AM, Smith AD. Cell cycle

In Search of γ-Secretase

• 5 Comments

05 May 1999

Peter Nelson, with Dennis Selkoe, John Hardy, and Alain Israel, led this live discussion on 5 May 1999. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion with Dennis Selkoe,