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Have you ever been jolted wide awake by—biostatistics? That’s what happened on the last morning of the Clinical Trials on Alzheimer’s Disease conference held November 5-7 in Barcelona, Spain. At 8 a.m., as sleepy CTADeers slowly shuffled in, Suzanne Hendr
DCE-MRI scans of six healthy young people, 18 older folks who were cognitively normal, and 21 older adults
knock-in mice were losing synapses. Beginning at 18 months, NL-F mice had trouble learning the location of
neocortical Aβ burden in Alzheimer’s disease: results from the AIBL study. Molecular Psychiatry (2013), 1–8
lengths for clinical trials of potential disease-modifying therapies in MCI would be one year, 18 months,
of Neuroligin 1. 18 Oct 2012;76:410-422. Free Access at Cell Press Peixoto R, Kunz PA, Kwon H, Mabb
cortex on [18]flurodeoxyglucose (FDG) positron emission tomography c) atrophy on MRI
18F-AV-45 (florbetapir F-18), an agent currently under consideration by the U.S. Food and Drug
number one genetic risk factor for late-onset Alzheimer’s disease (see AlzGene Top Results), yet 18 years
peptides, induces neuronal apoptosis. J Biol Chem. 2002 May 3;277(18):15666-70. Abstract Leon WC, Canneva F,
Alois Alzheimer made a major breakthrough when he discovered senile plaques in the brains of dementia patients, and his work ultimately led to the discovery of amyloid-β and to the amyloid cascade hypothesis. But that cascade is only part of a much bigger
On Thursday, 24 February 2011, Ruth Itzhaki, University of Manchester, U.K.; Elisa Porcellini, University of Bologna, Italy; Luc Letenneur, INSERM, Bordeaux, France, and Richard Smeyne, St. Jude Children’s Research Hospital, Memphis, Tennessee, shared som
This Webinar recapped the latest research in this area. Michael Heneka of the University of Bonn, Germany, and Doug Feinstein of the University of Illinois, Chicago, gave presentations, and were joined in a panel discussion by Virgil Muresan, New Jersey M
On 15 June 2009, we hosted a Webinar discussion with slide presentations by Ian McKeith at Newcastle University, UK, James Leverenz at University of Washington, Seattle, James Galvin, Washington University, St. Louis, Brit Mollenhauer of Paracelsus-Elena
but alters gene expression during aging. Cell. 2008 Nov 28;135(5):907-18. Abstract 0 Thursday,
Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.
