Schmidt V, Schulz N, Yan X, Schürmann A, Kempa S, Kern M, Blüher M, Poy MN, Olivecrona G, Willnow TE. SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity. J Clin Invest. 2016 Jul 1;126(7):2706-20. Epub 2016 Jun 20 PubMed.

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Research Models

  1. SORL1 transgenic (Cre-inducible)
  2. SORLA-deficient