Guerreiro R, Bilgic B, Guven G, Brás J, Rohrer J, Lohmann E, Hanagasi H, Gurvit H, Emre M. Novel compound heterozygous mutation in TREM2 found in a Turkish frontotemporal dementia-like family. Neurobiol Aging. 2013 Dec;34(12):2890.e1-5. Epub 2013 Jul 17 PubMed.

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Mutations

  1. TREM2 D86V
  2. TREM2 Y38C

Research Models

  1. Trem2 KO (JAX)
  2. Trem2 Y38C KI
  3. Trem2 KO (KOMP)
  4. Trem2 KO (KOMP) x htau
  5. Trem2 KO (Colonna)
  6. Trem2 KO (Colonna) x 5XFAD
  7. Trem2 KO (Colonna) x PS19