Picconi B, Centonze D, Håkansson K, Bernardi G, Greengard P, Fisone G, Cenci MA, Calabresi P. Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia. Nat Neurosci. 2003 May;6(5):501-6. PubMed.

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  1. These papers provide support for Parkinson's disease therapies and a basis for understanding L-DOPA's iatrogenic effects. It is curious that the GDNF recovery of function proceeded even as brain deterioration progressed.

    View all comments by Ruth Perez

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