Bian H, Van Swieten JC, Leight S, Massimo L, Wood E, Forman M, Moore P, de Koning I, Clark CM, Rosso S, Trojanowski J, Lee VM, Grossman M. CSF biomarkers in frontotemporal lobar degeneration with known pathology. Neurology. 2008 May 6;70(19 Pt 2):1827-35. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- FTD vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
- FTD vs AD : tau-total (CSF)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (CSF) |
AD (19) |
265.24 ± 110.72 pg/mL |
ELISA; Other/Not Specified; In-house |
|
| Aβ42 (CSF) |
CTRL- CNC (13) |
429.46 ± 133.83 pg/mL |
ELISA; Other/Not Specified; In-house |
|
| Aβ42 (CSF) |
FTD (19) |
533.42 ± 316.24 pg/mL |
ELISA; Other/Not Specified; In-house |
|
| tau-total (CSF) |
AD (19) |
522.56 ± 291.89 pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-total (CSF) |
CTRL- CNC (13) |
260.42 ± 93.75 pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-total (CSF) |
FTD (19) |
271.9 ± 149.81 pg/mL |
ELISA; Innotest; Innogenetics |
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