Grossman M, Farmer J, Leight S, Work M, Moore P, Van Deerlin V, Pratico D, Clark CM, Coslett HB, Chatterjee A, Gee J, Trojanowski JQ, Lee VM. Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease. Ann Neurol. 2005 May;57(5):721-9. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ42
(CSF)		 AD
(17)		 54 ± 15
pg/mL		 ELISA;
Other/Not Specified;
In-house
Aβ42
(CSF)		 CBS
(17)		 58.2 ± 28.4
pg/mL		 ELISA;
Other/Not Specified;
In-house		 Riley and , 1999
Aβ42
(CSF)		 CTRL-
CNC
(13)		 95 ± 30
pg/mL		 ELISA;
Other/Not Specified;
In-house
tau-p181
(CSF)		 AD
(17)		 73 ± 37
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-p181
(CSF)		 CBS
(17)		 53.6 ± 21.8
pg/mL		 ELISA;
Innotest;
Innogenetics		 Riley and , 1999
tau-p181
(CSF)		 CTRL-
CNC
(13)		 50 ± 14
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-total
(CSF)		 AD
(17)		 535 ± 304
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-total
(CSF)		 CBS
(17)		 106.5 ± 109.1
pg/mL		 ELISA;
Innotest;
Innogenetics		 Riley and , 1999
tau-total
(CSF)		 CTRL-
CNC
(13)		 260 ± 94
pg/mL		 ELISA;
Innotest;
Innogenetics

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This paper appears in the following:

News

  1. Research Brief: Bead-Based Biomarkers Neatly Divide AD, FTLD

AlzBiomarker

  1. AD vs CTRL : Aβ42 (CSF)
  2. CBS vs AD : Aβ42 (CSF)
  3. CTRL vs AD : Aβ42 (CSF)
  4. AD vs CTRL : tau-p181 (CSF)
  5. CBS vs AD : tau-p181 (CSF)
  6. CTRL vs AD : tau-p181 (CSF)
  7. AD vs CTRL : tau-total (CSF)
  8. CBS vs AD : tau-total (CSF)
  9. CTRL vs AD : tau-total (CSF)