Hori A, Ai T, Hato T, Inaba H, Tanaka K, Okamoto M, Horiuchi Y, Paran FJ, Tabe Y, Rosales C, Akamatsu W, Murayama T, Sakurai T, Miida T. Carvedilol suppresses ryanodine receptor-dependent Ca2+ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer's disease. 2023 Sep 16 10.1101/2023.09.15.558029 (version 1) bioRxiv.

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Mutations

  1. PSEN1 L286V