Lesné SE, Sherman MA, Grant M, Kuskowski M, Schneider JA, Bennett DA, Ashe KH. Brain amyloid-β oligomers in ageing and Alzheimer's disease. Brain. 2013 May;136(Pt 5):1383-98. PubMed. Correction.
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Lesné SE, Sherman MA, Grant M, Kuskowski M, Schneider JA, Bennett DA, Ashe KH. Brain amyloid-β oligomers in ageing and Alzheimer's disease. Brain. 2013 May;136(Pt 5):1383-98. PubMed. Correction.
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RIKEN Center for Brain Science
The group led by Karen Ashe presents an important finding that Aβ*56, not dimers or trimers, correlate with "pathological tau" proteins and postsynaptic proteins in human brains. Everyone in the AD research field should read this paper carefully and, if possible, try to validate the significance of the discovery.
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