Mielke MM, Hagen CE, Wennberg AM, Airey DC, Savica R, Knopman DS, Machulda MM, Roberts RO, Jack CR Jr, Petersen RC, Dage JL. Association of Plasma Total Tau Level With Cognitive Decline and Risk of Mild Cognitive Impairment or Dementia in the Mayo Clinic Study on Aging. JAMA Neurol. 2017 Sep 1;74(9):1073-1080. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
tau-total
(Plasma)		 MCI-AD
(27)		 4.7 ± 1.63
ng/L §		 SIMOA;
Other/Not Specified;
Quanterix		 Petersen, 2004; McKhann et al., 1984
tau-total
(Plasma)		 MCI-Stable
(65)		 4.1 ± 1.72
ng/L §		 SIMOA;
Other/Not Specified;
Quanterix		 Petersen, 2004

§ Data supplied to Alzforum by author

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