Raoul C, Estévez AG, Nishimune H, Cleveland DW, deLapeyrière O, Henderson CE, Haase G, Pettmann B. Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron. 2002 Sep 12;35(6):1067-83. PubMed.

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  1. A potential explanation for selective vulnerability of motoneurons in ALS. Whether the motoneurons cultured from embryos can be extended to other neurons in the body is unclear. The curious sparing of oculomotor neurons remains a big mystery to me.

    View all comments by Edward Koo

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