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Kester MI, Teunissen CE, Crimmins DL, Herries EM, Ladenson JH, Scheltens P, van der Flier WM, Morris JC, Holtzman DM, Fagan AM. Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease. JAMA Neurol. 2015 Nov;72(11):1275-80. PubMed.
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
neurogranin (CSF) |
MCI-AD (36) |
3219 ± 2098 pg/mL § |
Single Molecule Counting Immunoassay; Erenna; Singulex, Inc. |
|
neurogranin (CSF) |
MCI-Stable (17) |
1792 ± 991 pg/mL § |
Single Molecule Counting Immunoassay; Erenna; Singulex, Inc. |
Petersen et al., 1999 |
§ Data supplied to Alzforum by author
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