Antibody

MOAB-2 (6C3)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2aλ
Source: Millipore
Catalog #: MABN254
Formulation: Protein G purified; buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Reactivity:
Reacts in: Human
Availability: Confirmed available March 2015.

Immunogen/Epitope

Epitope maps to residues 1-4 of human Aβ42 and Aβ40 (DAEF)

Specificity

Reacts with the N-terminal end of Aβ (amino acids 1-4). Appears to detect monomeric, oligomeric, and fibrillar forms of Aβ. Greater sensitivity for Aβ42 than Aβ40. Does not cross react with holo-APP or APP-CTFs.

Note

Originally generated by Mary Jo LaDu and colleagues at the University of Illinois.

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References

Other Citations

  1. Mary Jo LaDu

Further Reading