Alzpedia
APP
Synonyms: (Amyloid Precursor Protein), amyloid beta (A4) precursor protein
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Alzpedia Citations
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News
- In Shout-Out for Community Studies, Vantaa Finds Protective Mutation
- Protective APP Mutation Found—Supports Amyloid Hypothesis
- Peer Pressure? "Pal" Leads APP Down Amyloid Path
- Inducible APP Mice—Cognition Restored in Advanced Amyloidosis?
- Coming Into Vogue? Retromer in APP Processing, AD Pathogenesis
- Cholesterol Binds APP Fragment, May Direct It to Lipid Rafts
- Case Dismissed—NIH Rescues JAX From APPswe Patent Suit
- Going It Alone—APP, BACE1 Take Distinct Routes to Endosome
Papers
- Haass C, Kaether C, Thinakaran G, Sisodia S. Trafficking and Proteolytic Processing of APP. Cold Spring Harb Perspect Med. 2012 May;2(5):a006270. PubMed.
- Müller UC, Zheng H. Physiological Functions of APP Family Proteins. Cold Spring Harb Perspect Med. 2012 Feb;2(2):a006288. PubMed.
- O'Brien RJ, Wong PC. Amyloid precursor protein processing and Alzheimer's disease. Annu Rev Neurosci. 2011;34:185-204. PubMed.
- Müller T, Meyer HE, Egensperger R, Marcus K. The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics-relevance for Alzheimer's disease. Prog Neurobiol. 2008 Aug;85(4):393-406. PubMed.